TGNET software has been widely used in the world, it can not only simulate the single pipeline transportation simple model, but also simulate the complex technology system contain multi supply, multi loop network, multi compressors, and multi valves, et. It was a long history software for gas transmission pipeline simulation. In order to play a guiding role in the operation of nature gas transmission pipeline by TGNET software, the actual production of Shuang 6 gas storage with the TGNET software was simulated. The simulation process included: The establishment of the pipeline gathering and transportation network model; Determined the gas model, the gas state equation and the friction coefficient formula. Shuang 6 gas storage input the basic parameters of the supply, gas pipeline and delivery; Start the simulation and output results. According to the simulation results, making a comparison table of the simulated pressure values and the measured pressure values of Shuang 6 gas storage, a comparison chart of pressure was drawn. The consequences showed that the relative error was less than 4.3% between the TGNET software simulation results and the actual production pressure, obtained the result of TGNET software that was suitable for the actual production situation of Liaohe oil field Shuang 6 gas storage.